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Shorter Telomeres Increase Risk for MS Disability Progression

Researchers found an association between telomere length and disability progression in multiple sclerosis. Biological age, as reflected in telomere length, is a risk factor for disability progression in multiple sclerosis (MS) beyond chronological age, according to a study published September 4 online in Annals of Neurology. The study indicates that those patients with shorter leukocyte telomeres are more likely to have higher disability scores and lower brain volume. “We found an association between telomere shortening and disability accumulation,” said lead study author Jennifer S. Graves, MD, PhD, MAS, assistant clinical professor of neurology at the University of California, San Francisc

Hyper-Long Telomeres Give Non-Genetically Modified Mice Longer, Healthier Lives

Images of fat, liver, and skin of adult mice with normal or hyper-long telomeres. In blue, nuclei; in red, telomeres. Telomeres of adult cells that are derived from the animals with the so-called hyper-long telomeres are brighter, indicating longer telomeres through adult life. /CNIO Mice with longer than normal telomeres in their species live, on average, 13% longer and in better health, free from cancer and obesity The study has found for the first time ever a clear relationship between the length of telomeres and insulin and glucose metabolism, which are also crucial in ageing “This finding opens the interesting hypothesis that genes are not the only thing to consider when it comes to det

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