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Titia de Lange to receive 2017 Rosenstiel Award

Titia de Lange, a biochemist who studies the protective ends of chromosomes known as telomeres, has been named the 2017 recipient of the Lewis S. Rosenstiel Award for Distinguished Work in Basic Medical Research, a highly prestigious honor presented annually by Brandeis University. She is recognized for her elucidation of the mechanism of telomere protection and the maintenance of genome stability.

de Lange, who is Leon Hess Professor and head of the Laboratory of Cell Biology and Genetics, is known for her discovery of the mechanisms by which telomeres repress DNA repair and damage responses that mistake chromosome ends for DNA breaks that need to be fixed. Her work has revealed how telomeres protect and preserve DNA, defining processes that are crucial for understanding the aging process and the development of diseases such as cancer.

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